By Davide Calamari, Roberto Marchetti
Water Research, Volume 7, Issue 10, October 1973, Pages 1453-1464, ISSN 0043-1354, DOI: 10.1016/0043-1354(73)90118-8.

The toxicity to rainbow trout of two metals (copper and mercury) and three detergents (two anionics and one non-ionic) were determined with an exposure period of 14 days. Each compound was tested separately and as a metal-detergent pair. The results show that for the mixtures of anionic detergents and metals a 'more-than-additive' effect exists, while for the mixture of non-ionic detergent and metal the toxic effect is probably 'less-than-additive'. These findings are compared with existing data in the literature and the underlying reasons for these effects are discussed.

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